miONCO-Dx
Xgenera has developed miONCO, a novel MCED which measures microRNA expression in a small amount of blood to identify the presence of cancer and its location in the body, with ground-breaking performance.
12 cancer types
Detects 68% of all new cancers
1 test=12 cancer
Detects 12 cancers in a single test
High sensitivity
99% sensitivity at each cancer stage
High specificity
99% specificity at each cancer stage
What are microRNAs?
MicroRNAs, or miRNAs, are small molecules in our cells that act as genetic regulators. They influence the expression of genes by binding to messenger RNA (mRNA), which carry instructions for making proteins. When miRNAs attach to mRNA, they can inhibit protein production. This regulation is vital for controlling various cellular processes, such as growth and development, and maintaining overall balance in our body's functions. Dysregulation of miRNAs can both contribute and be a symptom of disease such as cancer.
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We use miRNA to measure the tumour signal, the response of the host to the tumour and the signals that may drive tumourgenesis.
How can miRNAs be used to detect cancer?
We use a carefully curated panel of miRNAs that indicate cancer at the earliest stages. Our panel represents tumour initiation, tumour growth and host response which our machine learning process can interpret and predict cancer and its location.
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